St. Jude Children's Research Hospital Research Technologist - CRISPR-Cas Gene Editing in Memphis, Tennessee

The Tsai and Weiss Laboratories are seeking highly motivated and creative candidates for a Research Technologist to help develop potentially curative strategies to treat sickle cell disease by CRISPR-Cas gene editing of human hematopoietic stem cells for treatment of sickle cell disease.

You will have the opportunity to learn and support new projects such as:

  • Optimizing pre-clinical CRISPR-Cas gene editing strategies for induction of fetal hemoglobin in red blood cell progeny of edited human hematopoietic stem and progenitor cells

  • Developing improved genomic methods to define and measure genome-wide activity of gene editing nucleases

  • Protein engineering of CRISPR-Cas nucleases for precise gene correction

In this position, you will gain extensive experience and training in gene editing, protein engineering, and high-throughput genome biology.

To succeed in this position, you will have a strong molecular and cell biology background, with an emphasis on molecular cloning and genetic manipulation of mammalian cells. Applicants with experience with human hematopoietic stem cells, genome editing, next-generation sequencing, or automated liquid handling are strongly encouraged to apply.

Successful applicants will have excellent communication skills, and a B.S. or equivalent degree in molecular biology, cell biology, genetics, genomics, hematology, or a related area.

St. Jude is an Equal Opportunity Employer

No Search Firms:

St. Jude Children's Research Hospital does not accept unsolicited assistance from search firms for employment opportunities. Please do not call or email. All resumes submitted by search firms to any employee or other representative at St. Jude via email, the internet or in any form and/or method without a valid written search agreement in place and approved by HR will result in no fee being paid in the event the candidate is hired by St. Jude.

Posted Job Title: Research Technologist - CRISPR-Cas Gene Editing

WITS Req ID: 38278

Posted Department: Hematology