Alexion Pharmaceuticals Executive Director, US Sales, Complement, aHUS/PNH, West in Los Angeles, California

Position Summary

The Executive Director, US Sales – PNH/aHUS, West will be responsible for all sales activities related to PNH and aHUS for one third of the US market. He/she will lead a team of Regional Sales Directors in executing marketing strategies and achieving annual sales goals. This position reports to the VP of the US Complement Business Unit.

Principal Responsibilities

  • Leads one third of the US PNH/aHUS Sales team in achieving sales performance targets

  • Develops and ensures optimal execution of the national/territory sales plans; manages the annual budget accordingly

  • Hires, leads, coaches, develops, motivates and inspires the Sales Management Team

  • Actively review performance metrics with Regional Sales Directors and ensures timely and appropriate actions to address challenges and/or opportunities

  • Ensure the activities under responsibility meet the highest ethical standards, are in full compliance with the Alexion Code of Ethics and Business Conduct, and are in line with company policies and procedures

  • Collaborates closely with the ED US counterparts and PNH/aHUS Marketing Team to impact Marketing Plans and ensures that the US Marketing Plan is rolled out in alignment with Alexion’s key strategic imperatives.

  • Collaborates with Key Account Directors on strategic planning with key accounts and ensures best in class customer service to all accounts.

  • Creates, builds and maintains relationships with National Key Opinion Leaders in partnership with Marketing and Medical Affairs

  • Ensures operational systems are in place, enables RSDs to evaluate regional and territory sales activity and results

  • Ensures appropriate collaboration of US PNH/aHUS Sales team, Key Account Managers, Market Access, Case Management, Medical Science Liaison, and Customer Operations to optimize Alexion’s approach to meeting customer’s needs

  • Collaborates cross functionally with Global Sales and Marketing, Sales Training, Business Analytics, Sales Compensation Plans, Alignments, and Market Research

  • Takes a leadership role in development with US Incentive Compensation and Sales Effectiveness of Sales Compensation Plans

  • Play an active role in ongoing Senior Leadership Business Reviews through analysis and reporting of KPIs


  • Minimum of 15 years’ experience in the pharma and/or biopharma industry including significant experience managing pharma and/or biopharma sales teams in the US market

  • Experience in specialty pharma sales, preferably with, Hematology or Nephology disorders and/or orphan drug, with institutional, integrated delivery systems and community accounts

  • Successful track record of leading, developing and managing the performance of sales teams in delivering outstanding results

  • Demonstrated ability to convert business insights into actionable strategies to grow the business

  • Excellent communication skills with high learning agility and clear business and scientific acumen

  • Strong history of leadership, teamwork and cross functional collaboration that has resulted in significant accomplishments within an organization

  • Previous experience in one or more of the following areas an advantage: Marketing, Business Operations, Sales Training, Sales Force Effectiveness

  • Proven ability to work in a fast-paced, highly complex and challenging environment and lead ongoing change management as the organization continues to evolve

  • Ability to travel within the US on a regular basis which will include overnight and/or weekend travel with approximately 40% of time expected in Boston, HQ.


  • Bachelor’s Degree required; Master’s Degree preferred

  • Scientific background highly desirable


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Some opportunities happen only once in a lifetime - like a job where you have the extraordinary opportunity to change lives. At Alexion, such opportunities arise through our unwavering mission to serve patients and families affected by rare diseases. These patients are our guiding star, and we act with integrity, urgency, and discipline because we know their lives are at stake.

Alexion is a global biopharmaceutical company focused on serving patients and families affected by rare diseases through the discovery, development and commercialization of life-changing therapies. As the global leader in complement biology and inhibition for more than 20 years, Alexion has developed and commercializes the first and only approved complement inhibitor to treat patients with paroxysmal nocturnal hemoglobinuria (PNH), atypical hemolytic uremic syndrome (aHUS), and anti-acetylcholine receptor (AchR) antibody-positive generalized myasthenia gravis (gMG). Alexion also has two highly innovative enzyme replacement therapies for patients with life-threatening and ultra-rare metabolic disorders, hypophosphatasia (HPP) and lysosomal acid lipase deficiency (LAL-D). In addition, the company is developing two late-stage therapies, a second complement inhibitor and a copper-binding agent for Wilson disease. Alexion focuses its research efforts on novel molecules and targets in the complement cascade and its development efforts on the core therapeutic areas of hematology, nephrology, neurology, and metabolic disorders. Alexion has been named to the Forbes list of the World's Most Innovative Companies seven years in a row and is headquartered in Boston, Massachusetts' Innovation District. The company also has offices around the globe and serves patients in more than 50 countries.

Alexion's aspiration is to be the most rewarding place to work, where people are empowered to make a difference and where diversity of backgrounds and ideas is encouraged. We are looking for talented individuals who share our passion and commitment to change the lives of patients with rare diseases. We hope you will consider joining our team. Further information about Alexion can be found at:

As a leading employer in our industry, Alexion is proud to offer a highly competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, 401(k) with company match, tuition reimbursement, relocation assistance and much more.