Celgene Postdoc Fellow, Immunology in San Diego, California

Description

Celgene is a global biopharmaceutical company leading the way in medical innovation to help patients live longer, better lives. Our purpose as a company is to discover and develop therapies that will change the course of human health. We value our passion for patients, quest for innovation, spirit of independence and love of challenge. With a presence in more than 70 countries - and growing - we look for talented people to grow our business, advance our science and contribute to our unique culture.

Summary/Scope

We are seeking an experienced T-cell immunologist to investigate the role of PD-1 in T cell and Treg biology in the context of autoimmune diseases and understand the mechanism of action of therapeutics targeting this pathway. The successful applicant will have a strong background and publication record in immunology with a preference to a background in T-cell immunology. The applicant will be able to design and execute a variety of routine in vitro functional assays such as proliferation, cytokine secretion, T-reg assays, co-culture assays to measure cytotoxicity, and in-depth characterization of immune phenotype by flow cytometry to understand biology of pathways of interest. The applicant will also be working with in vivo models to understand the biological role of this pathway in various disease settings. The successful candidate will have the opportunity to work closely with discovery project teams and scientists and to present his or her work at project team meetings and to the senior research leadership. Industry experience is preferred but not essential.

Responsibilities will include, but are not limited to, the following:

  • Plan and execute experiments independently

  • Stay current with the literature in order to design experiments that address biological questions

  • Analyze, interpret and present scientific data

  • Interact with drug development team members to design experiments that can address mechanistic questions for the therapeutic of interest

  • Accurately maintain data and reports

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Qualifications

Skills/Knowledge Required:

  • Highly motivated scientist

  • PhD with 1-2 years of experience. PhD completed within last 3 years.

  • A deep understanding of T cell biology and general immunology

  • Experience with primary immune cell based assays, experience with T cell based assays, multiparameter flow cytometry, and molecular techniques

  • Experience with in vivo studies in disease or mechanistic models

  • Excellent communication, presentation and organizational skills

Celgene is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status.

Celgene complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Celgene in the U.S.

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Postdoc Fellow, Immunology

Location: San Diego, CA, US

Job ID: 17001225